Rapid switch from oral antiparkinsonian combination drug therapy to duodenal levodopa infusion
Identifieur interne : 002658 ( Main/Exploration ); précédent : 002657; suivant : 002659Rapid switch from oral antiparkinsonian combination drug therapy to duodenal levodopa infusion
Auteurs : Birgit Meiler [Allemagne] ; Jürgen Andrich [Allemagne] ; Thomas Müller [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2008-01.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Administration, Oral, Aged, Combined treatment, Drug Therapy, Combination, Drug combination, Duodenum, Female, Humans, Infusions, Parenteral, Jejunostomy, Levodopa, Levodopa (administration & dosage), Levodopa (therapeutic use), Male, Nervous system diseases, Oral administration, Parkinson Disease (drug therapy), Parkinson disease, Parkinson's disease, Time Factors, levodopa infusion.
- MESH :
- chemical , administration & dosage : Levodopa.
- chemical , therapeutic use : Levodopa.
- drug therapy : Parkinson Disease.
- Administration, Oral, Aged, Drug Therapy, Combination, Duodenum, Female, Humans, Infusions, Parenteral, Jejunostomy, Male, Time Factors.
Abstract
Six patients with Parkinson's disease (PD) with severe motor complications were directly switched from their oral antiparkinsonian combination drug regime to nasoduodenal levodopa infusion without previously recommended transient treatment with levodopa alone. Duodenal levodopa infusion reduced motor complications to a considerable extent. We have shown that a prior change to an oral levodopa monotherapy and a slow titration of duodenal levodopa infusion may be skipped and a direct switch to duodenal levodopa is a safe option. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21800
Affiliations:
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Le document en format XML
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<term>Drug combination</term>
<term>Duodenum</term>
<term>Female</term>
<term>Humans</term>
<term>Infusions, Parenteral</term>
<term>Jejunostomy</term>
<term>Levodopa</term>
<term>Levodopa (administration & dosage)</term>
<term>Levodopa (therapeutic use)</term>
<term>Male</term>
<term>Nervous system diseases</term>
<term>Oral administration</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>Time Factors</term>
<term>levodopa infusion</term>
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<term>Time Factors</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Association médicamenteuse</term>
<term>Duodénum</term>
<term>Lévodopa</term>
<term>Maladie de Parkinson</term>
<term>Pathologie du système nerveux</term>
<term>Traitement associé</term>
<term>Voie orale</term>
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<front><div type="abstract" xml:lang="en">Six patients with Parkinson's disease (PD) with severe motor complications were directly switched from their oral antiparkinsonian combination drug regime to nasoduodenal levodopa infusion without previously recommended transient treatment with levodopa alone. Duodenal levodopa infusion reduced motor complications to a considerable extent. We have shown that a prior change to an oral levodopa monotherapy and a slow titration of duodenal levodopa infusion may be skipped and a direct switch to duodenal levodopa is a safe option. © 2007 Movement Disorder Society</div>
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<name sortKey="Muller, Thomas" sort="Muller, Thomas" uniqKey="Muller T" first="Thomas" last="Müller">Thomas Müller</name>
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